Tammy McLoughlin Brady, MD, PhD

Professional Titles

• Vice Chair for Clinical Research, Department of Pediatrics
• Core Faculty, Welch Center for Prevention, Epidemiology, and Clinical Research
• Medical Director, Pediatric Hypertension Program

Primary Academic Title

Professor of Pediatrics

Background

Centers and Institutes

• Comprehensive Transplant Center
• Johns Hopkins Children's Center

Videos

• Arm Rest and Support Study (VIDEO), Johns Hopkins Clinical Connection, October 2024

Research Interests

Pediatric Hypertension

Lab Website

Obesity Hypertension Clinic: Reversing the Negative Cardiovascular Effects of Weight (ReNEW) - Lab Website

• Hypertension in children is a major cause of disease, including early onset heart disease. Up to 25% of children who are overweight or obese have hypertension (high blood pressure), and children with obesity are at greater risk for having other cardiovascular disease risk factors such as high cholesterol and diabetes. The ReNEW Clinic provides an innovative multidisciplinary approach to the evaluation and treatment of obesity-related hypertension to help prevent and treat cardiovascular disease. This clinic is designed for children with elevated blood pressure (prehypertension and hypertension) and a BMI at or above the 85th percentile.

Research Summary

Tammy Brady’s research is focused on promoting cardiovascular health across the patient lifespan. She has National Institutes of Health funding to determine the impact of dietary intake, mood disorders and adverse childhood experiences on cardiovascular disease risk factors in youth. 

Dr. Brady is part of a multidisciplinary team working on Resolve to Save Lives, an international campaign to decrease cardiovascular disease mortality worldwide. As part of this team, she has led two impactful clinical trials to study the effect of cuff size and resting on blood pressure measurement.

Dr. Brady directs a multidisciplinary obesity hypertension clinic called the Reversing the Negative cardiovascular Effects of Weight (ReNew) clinic. Many children in this clinic are enrolled in a longitudinal registry, which has formed the basis of several clinical investigations on how to better care for children with multiple risk factors for heart disease. In addition to her personal research efforts, Brady serves as vice chair for clinical research in the Department of Pediatrics.

Clinical Research

• NIH/NHLBI funded study:  Effect of Dietary Approaches on Vascular Function and Blood Pressure Phenotype in Youth
• NIH/NIMH funded study:  Association of Mood Disorders with Cardiovascular Disease Risk among Children and Adolescents

PubMed

http://www.ncbi.nlm.nih.gov/pubmed?term=Brady,%20Tammy[Full%20Author%20Name]&cmd=DetailsSearch

Selected Publications

• Brady, T, Schneider, M, Flynn, J, Cox, C, Samuels, J, Saland, J, White, C, Furth, S, Warady, B, Mitsnefes, M. Carotid Intima Media Thickness in Children with Chronic Kidney Disease: Results from the CKiD study. Clinical Journal of the American Society of Nephrology. 2012. (doi: 10.2215/CJN.03130312). Epub September 14, 2012. PMID:22977209

• Brady, TM, Appel, L, Holmes, KW., Fivush, BA, Miller, ER. The Association between Adiposity and Left Ventricular Mass in Children with Hypertension. J Clin Hypertens (Greenwich). 2015 Nov 4. doi: 10.1111/jch.12717. [Epub ahead of print]. PMID: 26530452.

• Brady, TM, Fivush, B, Flynn, JT, Parekh, R. Ability of Blood Pressure Parameters to Predict Left Ventricular Hypertrophy in Children with Primary Hypertension. J Pediatr 152(1):73-8,78.el, 2008. PMID:18154904

• Brady, TM, Solomon, BS, Neu, AM, Siberry, GK, Parekh, RS. Patient, Provider and Clinic Level Predictors of Unrecognized Elevated Blood Pressure in Children. Pediatrics 2010 Jun; 125 (6): e1286-e1293. PMID:20439598

• Reschke, LD, Miller, ER, Fadrowski, JJ, Loeffler, LF, Holmes, KW, Appel, L, Brady, T.M. Elevated Uric Acid and Cardiovascular Disease Risk among Hypertensive Youth. Pediatr Nephrol. 2015 Jul 2. [Epub ahead of print]. PMID 26135139

Honors

• Loan Repayment Program Award, National Institutes of Health, 7/1/14
• Leadership Program for Women Faculty, Johns Hopkins University School of Medicine, 1/1/13
• Loan Repayment Program Award, National Institutes of Health, 7/11/11
• Clinical Research Award, NEMA Research, 1/1/11
• Trainee Research Award - Best Clinical Abstract, American Society of Pediatric Nephrology, 1/1/07
• Best Clinical Abstract, Trainee Research Award, American Society of Pediatric Nephrology, 1/1/07
• Loan Repayment Program Award, National Institutes of Health, 7/1/06
• Pearl M. Stetler Fellowship Award, Research funding for woman physician, 1/1/06
• Clinical Scientist in Nephrology Fellowship Award, American Kidney Fund, 1/1/06
• Chief Residency, Pediatrics, Childrens Hospital at Montefiore, 1/1/03
• William J. Kenealy, S.J. Award, Awarded for distinction in academics and social concern, 1/1/96
• Order of the Cross and Crown, Awarded for high academic standing and an established record of service and leadership on campus, 1/1/96

Memberships

• American Society of Nephrology
• American Society of Pediatric Nephrology
• International Pediatric Hypertension Organization,

  U.S. Board Member, at Large, 2018

• National Kidney Foundation
• American Academy of Pediatrics
• Society for Pediatric Research

Professional Activities

• Accuracy in Measurement of Blood Pressure (AIM-BP) Collaborative, Member, 1/1/19
• American Heart Association, Validated Device Listing Independent Review Committee Member, 1/1/19
• American Heart Association, Member, 1/1/18
• American Society of Pediatric Nephrology, Research Committee, 1/1/09
• Association for the Advancement of Medical Instrumentation, Sphygmomanometer Committee, 1/1/14
• CKiD (Chronic Kidney Disease in Children) Cohort Study Consortium,, Cardiovascular Sub-Committee, 1/1/09
• National Kidney Foundation of Maryland, Medical Advisory Board Member, 1/1/14
• NEPTUNE (Nephrotic Syndrome Study Network) Pediatric Working Group, Cardiovascular Outcomes Committee and Recruitment and Retention Committee, 1/1/13