Liliana D. Florea, MSC, PhD
Highlights
Languages
- English
Gender
FemaleJohns Hopkins Affiliations:
- Johns Hopkins School of Medicine Faculty
About Liliana D. Florea
Primary Academic Title
Associate Professor of Genetic Medicine
Background
Dr. Liliana Florea is an Associate Professor of Medicine in the McKusick-Nathans Institute of Genetic Medicine, where she develops computational methods for analyzing large scale sequencing data to help characterize molecular mechanisms of diseases. Her research interests include comparing and analyzing genomes, characterizing genes and alternative splicing variations, and predicting non-coding RNA elements in human-virus interactions.
Before joining the Johns Hopkins faculty in 2011, Dr. Florea served on the faculty at the University of Maryland and the George Washington University. Previously, she was a member of the team of scientists at Celera Genomics that produced the first sequence of the human genome. Her work has been recognized with a Sloan Research Fellowship in Computational and Evolutionary Molecular Biology and has been funded by several NSF awards. Dr. Florea holds a PhD degree from the Pennsylvania State University.
Centers and Institutes
Additional Academic Titles
Associate Professor of Medicine
Contact for Research Inquiries
Phone: (443) 287-5624
Research Interests
Algorithms and tools for cDNA and genomic sequence alignment, Alternative splicing, Comparative and evolutionary genomics, Gene annotation, miRNA genomics and peptide-based vaccine design
Lab Website
Florea Lab Research - Lab Website
Core Facility
Selected Publications
Bao W, Florea L, Wu N, Wang Z, Banaudha K, Qian J, Houzet L, Kumar R, Kumar A. Loss of nuclear PTEN in HCV-infected human hepatocytes, Infectious Agents and Cancer, 2014; 9:23.
Eswaran J, Horvath A, Godbole S, Reddy SD, Mudvari P, Ohshiro K, Cyanam D, Nair S, Fuqua SAW, Polyak K, Florea LD, Kumar R. RNA sequencing of cancer reveals novel splicing alterations, Sci. Rep., 2013; 3:1689.?
Song L, Florea L. Rcorrector: efficient and accurate error correction for Illumina RNA-seq reads, GigaScience, 2015; 4:48.
Song L, Sabunciyan S, Florea L. CLASS2: Accurate and efficient splice variant annotation from RNA-seq reads, Nucl. Acids Res., 2016; 44(10):e98.
Walenz B, Florea L. Sim4db and leaff: Utilities for fast batch spliced alignment and sequence indexing. Bioinformatics, 2011; 27(13):1869-70.
Graduate Program Affiliations
Computational Biology Consulting Core