
Highlights
Johns Hopkins Affiliations:
- Johns Hopkins School of Medicine Faculty
About Antonio C. Wolff
Professional Titles
- Interim Director, Women's Malignancies Disease Group
Primary Academic Title
Professor of Oncology
Background
Dr. Antonio Wolff is a Professor of Oncology at Johns Hopkins University and is Director of Breast Cancer Trials in the Women’s Malignancies Program at the Johns Hopkins Kimmel Comprehensive Cancer Center. He is a practicing breast cancer medical oncologist and translational investigator with expertise in therapeutic clinical trials, biomarker development and implementation, survivorship, clinical practice guidelines, and quality initiatives. He is past member of American Society of Clinical Oncology’s Quality of Care Committee and past Chair of ASCO’s Clinical Practice Guidelines Committee. He is Panel Co-Chair and a lead author/senior author of the ASCO/College of American Pathology clinical practice guidelines on HER2 and hormone receptor testing in breast cancer. He has experience in collaborative, multidisciplinary national and international breast cancer clinical trials and on the integration of research findings into clinical practice. He serves as Chief Operating Officer of the Translational Breast Cancer Research Consortium. In 2009, he received an NCI Cancer Clinical Investigator Team Leadership Award. He serves as Chair of the ECOG-ACRIN Breast Cancer Committee and as member of the Breast Cancer Steering Committee as part of the NCI-funded National Clinical Trials Network (NCTN). He is a Fellow of ASCO and served as a Susan G. Komen Scholar between 2010-2021 and again as of 2023. He was identified in 2017 by Clarivate Analytics (Thomson Reuters) as one of the world’s most highly cited researchers (top 1% in clinical medicine). Dr. Wolff served as Associate Editor of Journal of Clinical Oncology between 2012-2022. At Johns Hopkins, he is a member of the Professorial Promotions Committee of the School of Medicine, and was inducted in 2018 in the JHU Miller Coulson Academy of Clinical Excellence. As part of the 125th anniversary celebration of the JHU School of Medicine, he was also recognized as one of 125 Living the Hopkins Mission Honorees, who were selected for their outstanding dedication to the institution’s core values of excellence and discovery, leadership and integrity, diversity and inclusion, and respect and collegiality.
Centers and Institutes
- Breast Health Services
- Johns Hopkins Green Spring Station
- Sidney Kimmel Comprehensive Cancer Center
X (Twitter)
Clinical Trial Keywords
breast cancer, biomarkers, survivorship
Videos
Research Interests
Breast Cancer
Selected Publications
Wolff AC, Blackford AL, Visvanathan K, Rugo HS, Moy B, Goldstein LJ, Stockerl-Goldstein K, Neumayer L, Langbaum TS, Theriault RL, Hughes ME, Weeks JC, Karp JE. Risk of marrow neoplasms after adjuvant breast cancer therapy: the national comprehensive cancer network experience. J Clin Oncol. 2015 Feb 1;33(4):340-8. doi: 10.1200/JCO.2013.54.6119. Epub 2014 Dec 22. PMID: 25534386
Wolff AC, Somerfield MR, Dowsett M, Hammond MEH, Hayes DF, McShane LM, Saphner TJ, Spears PA, Allison KH. Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer: ASCO-College of American Pathologists Guideline Update. J Clin Oncol. 2023 Jun 7:JCO2202864. doi: 10.1200/JCO.22.02864. Online ahead of print. PMID: 37284804
Kim HS, Umbricht CB, Illei PB, Cimino-Mathews A, Cho S, Chowdhury N, Figueroa-Magalhaes MC, Pesce C, Jeter SC, Mylander C, Rosman M, Tafra L, Turner BM, Hicks DG, Jensen TA, Miller DV, Armstrong DK, Connolly RM, Fetting JH, Miller RS, Park BH, Stearns V, Visvanathan K, Wolff AC, Cope L. Optimizing the Use of Gene Expression Profiling in Early-Stage Breast Cancer. J Clin Oncol. 2016 Dec 20;34(36):4390-4397. doi: 10.1200/JCO.2016.67.7195. Epub 2016 Oct 31. PMID: 27998227
Santa-Maria CA, Wolff AC. Antibody-Drug Conjugates in Breast Cancer: Searching for Magic Bullets. J Clin Oncol. 2023 Feb 1;41(4):732-735. doi: 10.1200/JCO.22.02217. Epub 2022 Nov 29. PMID: 36446052
Visvanathan K, Cope L, Fackler MJ, Considine M, Sokoll L, Carey LA, Forero-Torres A, Ingle JN, Lin NU, Nanda R, Storniolo AM, Tulac S, Venkatesan N, Wu NC, Marla S, Campbell S, Bates M, Umbricht CB, Wolff AC, Sukumar S. Evaluation of a Liquid Biopsy-Breast Cancer Methylation (LBx-BCM) Cartridge Assay for Predicting Early Disease Progression and Survival: TBCRC 005 Prospective Trial. Clin Cancer Res. 2023 Feb 16;29(4):784-790. doi: 10.1158/1078-0432.CCR-22-2128. PMID: 36534524
Honors
- Scholar, Susan G Komen Foundation, 4/1/23
- Member, JHU Miller Coulson Academy of Clinical Excellence, 4/1/18
- Recipient, NCI Cancer Clinical Investigator Team Leadership Award, 7/1/10
- Fellow, American Society of Clinical Oncology, 6/1/10
- Fellow, American College of Physicians, 7/1/04
Memberships
- American Society of Clinical Oncology
- European Society of Medical Oncology
Professional Activities
- ECOG-ACRIN Breast Cancer Committee, Chair, 1/1/18
- The Journal of Clinical Oncology, Associate Editor for Breast Cancer, 1/1/12 - 6/30/22
Locations
- Johns Hopkins Health Care & Surgery Center - Green Spring Station, Lutherville
- 10803 Falls Road, Pavilion III STE 1500, Lutherville, MD 21093
- phone: 410-583-2970
- fax: 410-583-2980
- Skip Viragh Outpatient Cancer Center
- 201 North Broadway Street, Viragh BLDG 10th FL, Baltimore, MD 21287
- phone: 410-955-8964
- fax: 410-367-2194
Expertise
Education
Johns Hopkins University School of Medicine
Fellowship, Medical Oncology, 1995Washington University School of Medicine
Fellowship, Hematology and Oncology, 1992The Mount Sinai Hospital
Residency, Internal Medicine, 1991MedStar Health
Residency, Internal Medicine, 1990Federal University of Rio de Janeiro
Medical Education, MD, 1986Board Certifications
Medical Oncology
American Board of Internal Medicine, 1995Insurance
- Aetna
- CareFirst
- Cigna
- First Health
- Geisinger Health Plan
- HealthSmart/Accel
- Humana
- Johns Hopkins Health Plans
- MultiPlan
- Pennsylvania's Preferred Health Networks (PPHN)
- Point Comfort Underwriters
- Private Healthcare Systems (PHCS)
- UnitedHealthcare
- Veteran Affairs Community Care Network (Optum-VACCN)
Ratings & Reviews
4.6 out of 5
66 ratings, 23 reviewsThe Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.
- 5 out of 5 starsReviewed on 2/20/2025
Excellent bedside manner. Good explanation of my condition and plan of care
- 5 out of 5 starsReviewed on 1/30/2025
Dr Wolff iz an excellent physician and one of the most compassionate that you could hope to be seen by.
- 5 out of 5 starsReviewed on 1/23/2025
He's amazing
- 5 out of 5 starsReviewed on 12/19/2024
Excellent , very on hands with me , down to earth
- 5 out of 5 starsReviewed on 12/19/2024
Dr. Wolff is incredibly compassionate. I always feel that he has genuine time for me and thoroughly listens.
- 5 out of 5 starsReviewed on 11/21/2024
I have the upmost respect for Dr.Wolff
- 5 out of 5 starsReviewed on 11/13/2024
I found Dr. Wolff to be very compassionate, knowledgeable, and patient
- 5 out of 5 starsReviewed on 9/25/2024
Professional, empathetic, knowledgable.
- 5 out of 5 starsReviewed on 8/29/2024
It was my first visit with Dr. Wolff (I was a patient of Dr. [ ] and he retired) and he was so great. Went through all my history, explained things, took time. I feel like I am in excellent hands!!!
- 5 out of 5 starsReviewed on 8/29/2024
Very caring- informed-reassuring
- 5 out of 5 starsReviewed on 8/29/2024
Excellent timely visit
- 5 out of 5 starsReviewed on 8/29/2024
Wonderful bedside manner - very caring
- 5 out of 5 starsReviewed on 8/28/2024
He is ao kind
- 5 out of 5 starsReviewed on 8/28/2024
Dr. Wolff is very easy to talk to about your concern and he takes into account your preferences for treatment. He is not rushed and he is very focused on patient education.
- 5 out of 5 starsReviewed on 8/13/2024
Dr. Wolff's assessment of my medical condition is very important to my treatment.
- 5 out of 5 starsReviewed on 7/30/2024
Good doctor - VERY poor at keeping timely appointments
- 5 out of 5 starsReviewed on 7/25/2024
Dr. Wolff is a compassionate, communicative, knowledgeable, extremely competent oncologist.
- 5 out of 5 starsReviewed on 7/18/2024
The appointment was perfect. Thank you.
- 5 out of 5 starsReviewed on 7/11/2024
Caring, kind and very knowledgeable
- 5 out of 5 starsReviewed on 6/20/2024
Dr. Wolff answered all my questions completely. I have complete confidence in his ability to provide excellent care and support.
- 5 out of 5 starsReviewed on 5/15/2024
I love my provider. However, I waited over an hour before my provider saw me after my appointment time. And then the time spent with him was very quickless than 15 minutes.
- 5 out of 5 starsReviewed on 4/17/2024
I had the best possible treatment from Dr. Wolff he went over all the new information that was in my chart good and not so good.
- 5 out of 5 starsReviewed on 4/16/2024
Excellent.