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Michael G. Goggins

Michael G. Goggins, MD

Gastroenterology

Accepting New Patients
Online Booking
4.9 of 5 stars41 ratings, 13 reviews
Johns Hopkins Affiliations:
  • Johns Hopkins School of Medicine Faculty

Languages

  • English

14 Insurances Accepted

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Gender

Male

About Michael G. Goggins

Primary Academic Title

Professor of Pathology

Background

Dr. Michael G. Goggins is a professor of pathology, medicine and oncology at the Johns Hopkins University School of Medicine. He serves as director of the Pancreatic Cancer Early Detection Laboratory and is an attending physician in medicine in the Division of Gastroenterology and Hepatology at The Johns Hopkins Hospital. He is the Sol Goldman Professor of Pancreatic Cancer Research.

Dr. Goggins’ research interests include developing tests to improve the early detection in pancreas cancer, evaluating outcomes of pancreatic surveillance and identifying gene variants responsible for inherited susceptibility to pancreatic cancer.

He obtained his medical degree in 1988 from Trinity College of the University of Dublin, Ireland. He completed a residency in internal medicine and a fellowship in Gastroenterology at St. James' Hospital in Dublin. He obtained his Membership of the Royal College of Physicians of Ireland in 1991 and his European Diploma in Gastroenterology in 1995. He joined the Johns Hopkins faculty in 1999.

Dr. Goggins is a member of the Royal College of Physicians of Ireland. He sits on the editorial boards of Gut.

Clinical Trials Summary

The Cancer of the Pancreas Screening-5 CAPS5)Study

http://clinicaltrials.gov/show/NCT02000089

Recent News Articles and Media Coverage

Additional Academic Titles

Professor of Medicine, Professor of Oncology

Research Interests

Early detection of pancreatic cancer, familial pancreatic cancer, markers of pancreatic cancer, pancreatic cancer epigenetics, pancreatic cancer genetics, pancreatic cancer screening

Lab Website

Early Detection of Pancreatic Cancer Laboratory - Lab Website

  • In the Pancreatic Cancer Early Detection Laboratory, Dr. Goggins oversees research that focuses on gene expression patterns of pancreatic cancers using microarray technology. The lab is also studying DNA methylation patterns looking for genes that are methylated in pancreatic cancer but not in normal cells.

    The lab has put together a profile of genes that are methylated in pancreatic cancer. Some pancreatic cancers methylate a lot of genes; most appear to methylate only a few genes. The lab is currently directing efforts to identify additional genes methylated in pancreatic cancer using novel techniques, and is studying the role of telomerase in pancreatic cancer and its potential as a marker for early detection.

Research Summary

Dr. Goggins’ current research is focused on discovering new markers of pancreatic adenocarcinoma using genetic, epigenetic and proteomic strategies, characterizing the epigenetic alterations in pancreatic cancers and normal tissues and identifying familial pancreatic cancer susceptibility genes through linkage, genome wide association and candidate gene approaches. Additional epigenetic studies are aimed at determining the functional and clinical significance of aberrant DNA methylation changes in pancreatic cancers.

Selected Publications

  • Goggins M, Overbeek KA, Brand R, Syngal S, Del Chiaro M, Bartsch DK, Bassi C, Carrato A, Farrell J, Fishman EK, Fockens P, Gress TM, van Hooft JE, Hruban RH, Kastrinos F, Klein A, Lennon AM, Lucas A, Park W, Rustgi A, Simeone D, Stoffel E, Vasen HFA, Cahen DL, Canto MI, Bruno M: Management of patients with increased risk for familial pancreatic cancer: updated recommendations from the International Cancer of the Pancreas Screening (CAPS) Consortium. Gut 2020, 69:7-17. doi: 0.1136/gutjnl-2019-319352. Epub 2019 Oct 31

  • Abe T, Blackford AL, Tamura K, Ford M, McCormick P, Chuidian M, Almario JA, Borges M, Lennon AM, Shin EJ, Klein AP, Hruban RH, Canto MI, Goggins M: Deleterious Germline Mutations Are a Risk Factor for Neoplastic Progression Among High-Risk Individuals Undergoing Pancreatic Surveillance. J Clin Oncol 2019, 37:1070-80

  • Abe T, Koi C, Kohi S, Song KB, Tamura K, Macgregor-Das A, Kitaoka N, Chuidian M, Ford M, Dbouk M, Borges M, He J, Burkhart R, Wolfgang CL, Klein AP, Eshleman JR, Hruban RH, Canto MI, Goggins M: Gene Variants That Affect Levels of Circulating Tumor Markers Increase Identification of Patients With Pancreatic Cancer. Clin Gastroenterol Hepatol 2020, 18:1161-9.e5. doi: 10.016/j.cgh.2019.10.036. Epub Oct 30

  • Blackford AL, Canto MI, Klein AP, Hruban RH, Goggins M: Recent trends in the incidence and survival of Stage 1A Pancreatic Cancer: A Surveillance, Epidemiology, and End Results analysis. J Natl Cancer Inst 2020, 112:1162-9

  • Tamura K, Yu J, Hata T, Suenaga M, Shindo K, Abe T, MacGregor-Das A, Borges M, Wolfgang CL, Weiss MJ, He J, Canto MI, Petersen GM, Gallinger S, Syngal S, Brand RE, Rustgi A, Olson SH, Stoffel E, Cote ML, Zogopoulos G, Potash JB, Goes FS, McCombie RW, Zandi PP, Pirooznia M, Kramer M, Parla J, Eshleman JR, Roberts NJ, Hruban RH, Klein AP, Goggins M: Mutations in the pancreatic secretory enzymes CPA1 and CPB1 are associated with pancreatic cancer. Proc Natl Acad Sci U S A 2018, 115:4767-72

Graduate Program Affiliations

  • Pathology

    Pathobiology

Memberships

  • European Board of Gastroenterology
  • Royal College of Physicians of Ireland

Locations

  1. Johns Hopkins Health Care & Surgery Center - Green Spring Station, Lutherville
    • 2360 West Joppa Road, Joppa Concourse STE 205, Lutherville, MD 21093

    Expertise

    Education

    Johns Hopkins University School of Medicine

    Fellowship, 1998

    St James's Hospital

    Fellowship, Internal Medicine, 1995

    St James's Hospital

    Residency, Medicine, 1991

    St James's Hospital

    Residency, 1989

    University of Dublin Trinity College

    Medical Education, MD, 1988

    Insurance

    Johns Hopkins providers accept various commercial health insurance plans. However, they may not be included in all of an insurance company's plans or offerings. This may include Exchange, Medicaid, Medicare, and specific limited benefit plans. Exceptions to participation also exist based on your employer’s benefits package and the provider's location or specialty. Please contact your insurer directly to make sure your doctor is covered by your plan. For more details, please review our Insurance Information.
    Search plans
    • Aetna
    • CareFirst
    • Cigna
    • First Health
    • Geisinger Health Plan
    • HealthSmart/Accel
    • Humana
    • Johns Hopkins Health Plans
    • MultiPlan
    • Pennsylvania's Preferred Health Networks (PPHN)
    • Point Comfort Underwriters
    • Private Healthcare Systems (PHCS)
    • UnitedHealthcare
    • Veteran Affairs Community Care Network (Optum-VACCN)

    Ratings & Reviews

    4.9 out of 5

    41 ratings, 13 reviews

    The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

    Overall Rating by Patient
    Average provider Overall Rating by Patient rating 4.9 out of 5 stars
    Provider Listened Carefully
    Average provider Provider Listened Carefully rating 5 out of 5 stars
    Provider Explained Things Clearly
    Average provider Provider Explained Things Clearly rating 5 out of 5 stars
    Provider Knew Medical History
    Average provider Provider Knew Medical History rating 4.9 out of 5 stars
    Provider Showed Respect
    Average provider Provider Showed Respect rating 5 out of 5 stars
    Provider Spent Enough Time
    Average provider Provider Spent Enough Time rating 5 out of 5 stars
    Search reviews
      5 out of 5 stars
      Reviewed on 12/10/2024

      Excellent in every way! Brilliant, thorough and informative.

      5 out of 5 stars
      Reviewed on 10/22/2024

      Pleasant, clear, will informed about my situation, gave alternatives as well as providing clear guidance to best decision

      5 out of 5 stars
      Reviewed on 10/8/2024

      Knowledgeable, good listener and communicator

      4 out of 5 stars
      Reviewed on 10/8/2024

      Very knowledgeable

      5 out of 5 stars
      Reviewed on 10/8/2024

      Dr. Goggins and I had a good initial meeting as I joined his Pancreatic Cancer for Braca 1 Positive individuals. He was very considerate when he found out I needed to postpone my endoscopy due to a Cervical Fusion I was having and had to postpone the endoscopy for 3 months. It made me feel like I was valued for his study.

      5 out of 5 stars
      Reviewed on 9/24/2024

      Excellent

      5 out of 5 stars
      Reviewed on 9/24/2024

      For being the first provider and I have never met him I really like him. He really listens to what you have to say.

      5 out of 5 stars
      Reviewed on 8/13/2024

      Dr. Goggins is an extremely patient doctor. I am an anxious person and probably repeated myself with questions several times and he was very patient and assuring.

      5 out of 5 stars
      Reviewed on 5/28/2024

      This was my first video call with Dr. Goggins. He was very respectful and thorough, and transparent during our conversation.

      5 out of 5 stars
      Reviewed on 5/14/2024

      Happy with provider per se, BUT making aptm & accessing location VERY DIFFICULT!

      5 out of 5 stars
      Reviewed on 4/23/2024

      I feel lucky to be able to get care from a doctor of this caliber without being rich or famous.

      5 out of 5 stars
      Reviewed on 4/23/2024

      Dr. Goggins has excellent patient and understanding expertise; is a knowledgeable and thorough physician.

      5 out of 5 stars
      Reviewed on 4/9/2024

      This was my first meeting with Dr. Goggins and he is terrific ... Knowledgable, thorough, compassionate.