Jean Kim, MD, PhD

Primary Academic Title

Associate Professor of Otolaryngology-Head and Neck Surgery

Background

Centers and Institutes

• Asthma and Allergy Center
• Jerome L. Green Sjogren's Syndrome Center
• Sinus Center
• Vasculitis Center

Clinical Trial Keywords

Epithelium and Chronic Rhinosinusitis; Mechanism of Host Defense in Chronic Rhinosinusitis

Videos

• Meet our Expert - Dr. Jean Kim

• Sinus Surgery: Nici's Story

• Tackling Severe Sinus Disease with a Multidisciplinary Approach | Rex‚Äôs Story

• Abstract: Therapeutic Potential of Dupilumab in the Treatment of Chronic Rhinosinusitis with Nasal Polyps

• Climate Change, the Environment and Rhinologic Disease

Recent News Articles and Media Coverage

• Clinicians’ Review of Scientific Studies Underscores Links Between Climate Change and Nose and Sinus Conditions, Hopkins Medicine, (02/06/2023)

  With Basic Biology and Clinical Savvy, Scientists Solve A Mystery in The Nose, Fundamentals (Sept/Oct 2021)

  Researchers ID Anti-Inflammatory Proteins as Therapy Targets for Nasal and Sinus (6/9/2021)

  Raising Awareness of AERD, HeadLines (Winter 2020)

  Recorded Online Seminar: Thinking of Sinus Surgery?

Additional Academic Titles

Associate Professor of Medicine

Research Interests

clinical, translational, and basic science research in autoimmune sinusitis and salivary gland disease. This includes Epithelial cell dysfunction of the upper airways, Clinical, translational, and basic science research in chronic rhinosinusitis and nasal polyposis, Gene regulation of cytokine expression, immune dysfunction and upper airway epithelial cell biology, Molecular mechanisms of host defense in chronic rhinosinusitis

Lab Website

Jean Kim Lab

• The Jean Kim Laboratory performs translational research in the area of chronic rhinosinusitis, with a niche interest in the pathogenesis of hyperplastic nasal polyposis. Studies encompass clinical research to basic wet laboratory research in studying the underlying immune and autoimmune mediated mechanism of polyp growth and perpetuation of disease. Human cell and tissue culture models are used. Techniques in the laboratory include cell and tissue culture, real time PCR, immunoblot, ELISA, flow cytometry, immunohistochemistry, electron microscopy, gene array analysis, and other molecular approaches including genetic knockdowns. Approaches used in Dr. Kim's clinical study designs include prospective and retrospective analysis of patient outcomes and clinical biomarkers, as wells controlled clinical trials.

Selected Publications

• The Relationship of Climate Change to RhinitisThe Journal of Allergy and Clinical Immunology in Practice Jean Kim, Philip W. Rouladi

• Induction of the endogenous sialoglycan ligand for eosinophil death receptor Siglec-8 in chronic rhinosinusitis with hyperplastic nasal polyposis Glycobiology Hyun Sil Lee, Anabel Gonzalez-Gil, Virginia Drake, T August Li, Ronald L Schnaar, Jean Kim. 

• Biologics for chronic rhinosinusitis with nasal polyps: Economics and ethics

  International Forum of Allergy & Rhinology

  Lauren T. Roland MD, MSCI,Alan Regenberg MBE,Amber U. Luong MD, PhD,Sarah K. Wise MD, MSCR,Elina Toskala MD, PhD, MBA,Kent K. Lam MD,Joshua M. Levy MD, MPH,Christine B. Franzese MD,Kristine Smith MD,Jean Kim MD, PhD

  https://doi.org/10.1002/alr.22864

   

• Kim, J, Waugh, DW, Zaitchik, BF, et al. Climate change, the environment, and rhinologic disease. Int Forum Allergy Rhinol. 2022; 1- 12. https://doi.org/10.1002/alr.23128

• Kim, J., M.Z. Cheng, and R. Naclerio, Management of the Upper Airway Distress During Pregnancy. Immunology and Allergy Clinics of North America, 2022. https://doi.org/10.1016/j.iac.2022.05.010

Memberships

• Fellow of American College of Surgeons- FACS
• Fellow of American Rhinologic Society- FARS
• Fellow of American Academy of Asthma Allergy and Clinical Immunology-FAAAI