Deborah Persaud, MD
Pediatric Infectious Diseases
- Johns Hopkins School of Medicine Faculty
About Deborah Persaud
Professional Titles
- Director, Pediatric Infectious Diseases
Primary Academic Title
Professor of Pediatrics
Background
Dr. Deborah Persaud is a professor of pediatrics at the Johns Hopkins University School of Medicine, and the director of the Division of Pediatric Infectious Diseases at Johns Hopkins Children's Center. She holds joint appointments in international health and molecular microbiology and immunology at the Johns Hopkins Bloomberg School of Public Health.
A clinician and researcher specializing in the study and treatment of HIV-1 infection in children, she directs the pediatric infectious diseases fellowship program at the Johns Hopkins Children’s Center.
Dr. Persaud received her B.S. in chemistry from York College in New York. A 1985 graduate of the New York University School of Medicine, she trained in pediatrics at Babies Hospital/Columbia Presbyterian Medical Center in New York, where she was chief resident. She was an infectious disease fellow, an Aaron Diamond postdoctoral research fellow and a faculty member at New York University. She joined the Johns Hopkins faculty in 1997, following a visiting lectureship at the Moi University in Eldoret, Kenya.
Her research interests include HIV/AIDS drug development and mother-to-child HIV transmission.
Dr. Persaud is the scientific chair of the HIV CURE Scientific Committee of the International Maternal, Pediatric Adolescent AIDS Clinical Trials (IMPAACT) group. She was awarded the prestigious Elizabeth Glaser Scientist Award for her HIV research and was recognized by Nature magazine in 2013 as one of “Ten People Who Mattered This Year.” She was recognized by Time magazine as among the “100 Most Influential People of 2013” for her pediatric HIV treatment research.
Centers and Institutes
CV
http://www.hopkinsmedicine.org/johns-hopkins-childrens-center/_documents/_cvs/persaud_deborah_cv.pdf
Recent News Articles and Media Coverage
Early Treatment Is Found to Clear H.I.V. in a 2nd Baby, The New York Times, March 5, 2014
Research Interests
HIV latency, HIV pathogenesis and cure therapeutics for infants, children and adolescents, Mother-to-child HIV transmission, SARS-CoV-2 pathogenesis in children
Research Summary
Dr. Persaud’s research focuses on the immunopathogenesis of HIV latency in perinatal infections in infants, children, and adolescents towards improving HIV therapeutics for this population with the goal of eventual HIV remission and cure. She oversees the development of the clinical trials pipeline for HIV cure therapeutics for the NIH-sponsored International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Network. Her laboratory is also a sub-specialty laboratory for NIH-sponsored HIV prevention and cure clinical trials targeting perinatal and adult HIV infections.
Selected Publications
Persaud D, Gay H, Ziemniak C, Chen YH, Piatak M Jr, Chun TW, Strain M, Richman D, Luzuriaga K. Absence of Detectable Viremia after Treatment Cessation in an Infant. NEJM. 2013;7;369 (19):1828-35. PMID:24152233;PMCID PMC 3954754; NIHMS542777
Brumme ZL, Sudderuddin H, Ziemniak C, Luzuriaga K, Jones BR, Joy JB, Cunningham CK, Greenough T, Persaud D. Genetic complexity in the replication-competent latent HIV reservoir increases with untreated infection duration in infected youth. AIDS. 2019 Feb 1;33(2):211-218. PMID:30325763
Dhummakupt A, Rubens JH, Anderson T, Powell L, Nonyane BA, Siems LV, Collinson-Streng A, Nilles T, Jones RB, Tepper V, Agwu A, Persaud D. Differences in inducibility of the latent HIV reservoir in perinatal and adult infection. JCI Insight. 2020 Feb 27;5(4). PMID: 31999647
Uprety, P., Patel, K., Karalius, B., Ziemniak, C., Hui, Y.C., Brummel, S.S., Siminski, S., Van Dyke, R.B., Seage III, G.R., Persaud, D. HIV-1 DNA Decay Dynamics with Early, Long-term Virologic Control of Perinatal Infection. CID, 2017; 64 911); 1471-1478. PMID 28329153
Honors
- 100 Most Influential People, Time, 1/1/13
- Ten People Who Mattered This Year, Nature, 1/1/13
- Elizabeth Glaser Scientist Award, 1/1/05
- Doris Duke Clinician Scientist Award, 1/1/99
Memberships
- Infectious Diseases Society of America
- Pediatric Infectious Diseases Society
- International AIDS Society
Professional Activities
- HIV Cure Scientific Committee for the International Maternal, Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Network, Chair
- Immunology, Virology and Vaccine Subcommittee for the Pediatric AIDS Clinical Trials Group, Committee Member, 1/1/01
- International AIDS Society Industry Collaborative Group, Co-Chair, 1/1/20
Locations
- Rubenstein Child Health Building
- 200 North Wolfe Street, Rubenstein BLDG Lower Level, Baltimore, MD 21287
- phone: 443-997-5437
- fax: 410-955-1491
Expertise
Education
NYU Langone Medical Center
Fellowship, Pediatric Infectious Diseases, 1992New York-Presbyterian Columbia
Residency, Pediatrics, 1989New York University School of Medicine
Medical Education, MD, 1985Board Certifications
Pediatric Infectious Diseases
American Board of Pediatrics, 1994Insurance
- Aetna
- CareFirst
- Cigna
- First Health
- Geisinger Health Plan
- HealthSmart/Accel
- Humana
- Johns Hopkins Health Plans
- MultiPlan
- Pennsylvania's Preferred Health Networks (PPHN)
- Point Comfort Underwriters
- Private Healthcare Systems (PHCS)
- UnitedHealthcare
- Veteran Affairs Community Care Network (Optum-VACCN)