Ann Scheimann, MD

Professional Titles

• Medical Advisor, Weight Management Program

Primary Academic Title

Professor of Pediatrics

Background

Centers and Institutes

• Comprehensive Transplant Center
• Johns Hopkins Children's Center
• Meyerhoff Inflammatory Bowel Disease Center
• Pediatric Liver Center

CV

http://www.hopkinsmedicine.org/johns-hopkins-childrens-center/_documents/_cvs/scheimann_ann_cv.pdf

Research Interests

Non-alcoholic fatty liver disease, Prader-willi Syndrome, obesity

Research Summary

Dr. Scheimann’s research focuses on non-alcoholic fatty liver disease, obesity and Prader-Willi syndrome in children.

Selected Publications

• Allander SV, Durham SK., Scheimann AO, Wasserman RM, Suwanichkul A, Powell DR. Hepatic Nuclear Factor 3 and High Mobility Group I/Y Proteins Bind the Insulin Response Element of the Insulin-like Growth Factor-binding protein-1 Promoter, Endocrinology, 1997;138(10): 4291-300.

• Durham SK., Suwanichkul A, Scheimann AO., Yee D, Jackson JG., Barr FG., Powell DR. FKHR Binds the Insulin Response Element in the Insulin-like Growth Factor Binding-protein-1 Promoter, Endocrinology, 1999;140(7): 3140-6.

• Ellis KJ., Scheimann AO, Lee, PDK. Body Composition Measurements: Application in Prader-willi Syndrome, The Endocrinologist, July 2000, 10(4): 57S-63S.

• Hourigan SK, Abrams S, Yates K, Pfeifer K, Torbenson M, Murray K, Roth CL, Kowdley K, Scheimann AO; NASH CRN. “Relation between vitamin D status and nonalcoholic fatty liver disease in children.” J Pediatr Gastroenterol Nutr. 2015 Mar;60(3):396-404. doi: 10.1097/MPG.0000000000000598.

• Hourigan SK, Torbenson M, Tibesar E, Scheimann AO. “The full spectrum of hepatic steatosis in children.” Clin Pediatr (Phila). 2015 Jan 7. pii: 0009922814566927.

• Powell, DR., Allander, SV., Scheimann, AO., Wasserman, RM., Durham, SK., Suwanichkul, A. Multiple Proteins Bind the Insulin Response Element in the Human IGFBP-1 Promoter. Progress in Growth Factor Research, 1995 6(2-4):93-101.

• Scheimann AO, Butler MG, Cuffari C, Gourash L, Klish W. Critical Analysis of Bariatric Procedures in Prader-willi Syndrome. JPGN (in press).

• Scheimann AO, Durham SK, Suwanichkul A, Snuggs MB, Powell DR. The Role of Three FKHR Phosphorylation Sites in Insulin Inhibition of FKHR Action in Hepatocytes. Hormone Metabolic Research, 2001 November; 33: 631-8.

• Scheimann AO, Strautnieks SS, Knisely AS, Byrne JA,Thompson R, Finegold M. Mutations in Bile Salt Export Pump (ABCB11) in Two Children with Progressive Familial Intrahepatic Cholestasis and Cholangiocarcinoma. J Pediatr. 2007 May;150(5):556-9.

• Schwimmer JB, Zepeda A, Newton KP, Xanthakos SA, Behling C, Hallinan EK, Donithan M, Tonascia J; Nonalcoholic Steatohepatitis Clinical Research Network. “Longitudinal assessment of high blood pressure in children with nonalcoholic fatty liver disease.” PLoS One. 2014 Nov 24;9(11):e112569. doi: 10.1371/journal.pone.0112569. eCollection 2014.

• Stevenson DA, Heineman J, Angulo M, Butler MG, Loker J, Kendell P, Cassidy S, Scheimann AO. Gastric Rupture and Necrosis in Prader-willi Syndrome. J Pediatr Gastro Nutr 2007;45:272-4.

• Stevenson DA, Heinemann J, Angulo M, Butler MG, Loker J, Rupe N, Kendell P, Clericuzio CL, Scheimann AO. Deaths Due to Choking in Prader-Willi Syndrome. Am J Med Genet A. 2007 Mar 1;143(5):484-7.

• Tibesar E, Karwowski C, Hertel P, Scheimann A, Karnsakul W. “Two cases of progressive familial intrahepatic cholestasis type 2 presenting with severe coagulopathy without jaundice.” Case Rep Pediatr. 2014;2014:185923. doi: 10.1155/2014/185923. Epub 2014 Jun 2.

• Vasilescu A, Cuffari C, Santo Domingo L, Scheimann AO. “Predictors of severity in childhood pancreatitis: correlation with nutritional status and racial demographics.” Pancreas. 2015 Apr;44(3):401-3. doi: 10.1097/MPA.0000000000000281.

• Williams K, Scheimann A, Sutton V, Hayslett E, Glaze D. Sleepiness and Sleep Disordered Breathing in Prader-willi Syndrome: Relationship to Genotype, Growth Hormone Therapy and Body Composition. Journal of Clinical Sleep Medicine (in press).

Honors

• International Scientific Advisory Board for the International Prader-willi Syndrome Association, 1/1/07
• Grant Award, Mt. Washington Pediatric Foundation, 1/1/05
• National Scientific Advisory Board for the Prader-willi Syndrome Association, 1/1/02
• Accepted for Membership in the American Association for the Advancement of the Study of Liver Disease, 1/1/02
• Clinical Fellowship Grant, Cystic Fibrosis Foundation, 1/1/93
• Service Award, University of Cincinnati College of Medicine Alumni Association, 1/1/90
• Bob Swain Service Award, University of Cincinnati College of Medicine, 1/1/88
• Montgomery County Medical Society Award, University of Dayton, 1/1/86
• Brother Molz Memorial Service Award, University of Dayton, 1/1/86
• Whisman Academic Scholarship to the University of Cincinnati College of Medicine, 1/1/86

Lectures & Presentations

Childhood Obesity: A Crisis in Healthcare, Pediatric Grand Rounds, Johns Hopkins Hospital, Baltimore, MD, 1/1/05

Memberships

• American Association for the Advancement of the Study of Liver Disease
• North American Society for Pediatric Gastroenterology, Hepatology and Nutrition
• Prader-Willi Syndrome Association
• American Society for Parenteral and Enteral Nutrition
• Obesity Society

Professional Activities

• Data Safety Monitoring Committee, Peds C Study, National Institutes of Health, Chair, 1/1/10
• International Hyperphagia Conference, Co-chair, 1/1/09
• National Convention, Prader-Willi Syndrome Association, Co-chair, 1/1/06 - 1/1/07
• National Scientific Meeting, Prader-Willi Syndrome Association, Co-chair, 1/1/07
• NIH, Pediatric principal investigator, 1/1/02 - 1/1/08
• Pediatrics and Therapeutics, Editorial Board
• Planning Committee, Pediatric Nutrition Symposia, NASPGHAN, Chairperson, 1/1/11
• Prader-Willi Syndrome Association, National Scientific Advisory Board, 1/1/02
• World Journal of Hepatology, Editorial Board